abstract：:Plasma concentrations of motilin, gastrin, and enteroglucagon were measured in cord blood and during the first 24 days of life before feeding in 45 term and 63 preterm, healthy infants. Levels of these hormones rose steeply after birth, reaching concentrations that were much higher than those in fasting adults. These ...

journal_title：Archives of disease in childhood

authors： Lucas A,Adrian TE,Christofides N,Bloom SR,Aynsley-Green A

更新日期：1980-09-01 00:00:00

abstract：:A 20-year-old woman with untreated homocystinuria was examined when she was 18 weeks' pregnant. Amniocentesis was performed and raised levels of homocystine and methionine were present in the amniotic fluid. Assay of cystathionine synthetase activity in cultured amniotic fluid cells showed the carrier state for homocy...

journal_title：Archives of disease in childhood

authors： Kurczynski TW,Muir WA,Fleisher LD,Palomaki JF,Gaull GE,Rassin DK,Abramowsky C

更新日期：1980-09-01 00:00:00

abstract：:During a screening programme of 10000 pregnant women by the Guthrie test, a previously unrecognised phenylketonuric woman was detected. A low phenylalanine diet introduced from the 16th week of gestation failed to prevent fetal abnormality and mental retardation. Maternal phenylketonuria requires earlier diagnosis tha...

journal_title：Archives of disease in childhood

authors： Scott TM,Fyfe WM,Hart DM

更新日期：1980-08-01 00:00:00

abstract：:The fetal heart beat, detected by ultrasound, was recorded for five minutes from 934 antenatal women--266 at 30 to 35 weeks' gestation and 718 at 36 to 41 weeks. Episodes of bradycardia < 100/minute ranging from 5-30 seconds' duration occurred in 3 (1.1%) of the former and in 9 (1.3%) of the latter group. Tachycardia ...

journal_title：Archives of disease in childhood

authors： Southall DP,Richards J,Hardwick RA,Shinebourne EA,Gibbens GL,Thelwall-Jones H,de Swiet M,Johnston PG

更新日期：1980-07-01 00:00:00

abstract：:The serum concentrations of the phagocytosis-stimulating peptide, tuftsin, were determined by radioimmunoassay in 21 patients with sickle cell disease and in 12 healthy controls. The mean serum tuftsin concentration was significantly lower in patient with haemoglobin SS disease (154.3 +/- 35.1 ng/ml; 308.6 +/- 70.2 nm...

journal_title：Archives of disease in childhood

authors： Spirer Z,Weisman Y,Zakuth V,Fridkin M,Bogair N

更新日期：1980-07-01 00:00:00

abstract：:19 young children (less than 5 years old) have received 31 renal transplants from 4 live relatives and 27 cadaver donors. The 2-year allograft survival rate for the patients receiving their 1st allograft from the 4 live donors was 75 +/- 22% while for the patients receiving their 1st allograft from 15 cadaver donors w...

journal_title：Archives of disease in childhood

authors： Rizzoni G,Malekzadeh MH,Pennisi AJ,Ettenger RB,Uittenbogaart CH,Fine RN

更新日期：1980-07-01 00:00:00

abstract：:Two siblings were born with congenital heart block, and one suffered from severe hydrops fetalis, although maintaining a higher heart rate than the other. The association of hydrops fetalis with disorders of cardiac rhythm is unlikely to be simply a manifestation of congestive cardiac failure in the fetus. ...

journal_title：Archives of disease in childhood

authors： Cooke RW,Mettau JW,Van Cappelle AW,de Villeneuve VH

更新日期：1980-06-01 00:00:00

abstract：:The family histories relating to asthma and wheezy bronchitis were examined in 77 asthmatic, 78 wheezy bronchitic, and 87 control children, aged between 1 and 12 years. The percentage of children with at least one asthmatic relative was significantly greater in the asthmatic and wheezy bronchitic probands than in the ...

journal_title：Archives of disease in childhood

authors： Sibbald B,Horn ME,Gregg I

更新日期：1980-05-01 00:00:00

abstract：:An infant with lactose intolerance is described. A breast-fed infant developed vomiting at 3 weeks, and became dehydrated. Lactosuria, aminoaciduria, and liver damage were preesent. A milk-free diet led to rapid recovery. At 6 months a normal diet was well tolerated. ...

journal_title：Archives of disease in childhood

authors： Hosková A,Sabacký J,Mrskos A,Pospísil R

更新日期：1980-04-01 00:00:00

abstract：:Dubowitz et al. have offered a scoring system for estimating the gestational age of newborn babies. If the system is applied to twin pairs, the heavier twin is generally estimated to have a greater gestational age than the lighter one. Previously this has been interpreted as a flaw in the scoring system. However, it m...

journal_title：Archives of disease in childhood

authors： James WH

更新日期：1980-04-01 00:00:00

abstract：:Of the 265 children aged between 6 and 18 months admitted to hospital in a 26-month period each with his first febrile convulsion, there were 64 who satisfied our criteria for a simple febrile convulsion. Of these, 43 (random) were entered into a double-blind trial of continuous sodium valproate versus phenobarbitone,...

journal_title：Archives of disease in childhood

authors： Ngwane E,Bower B

更新日期：1980-03-01 00:00:00

abstract：:A 14-month-old girl with invasive perineal amoebiasis is reported. There was destruction of the anus, the rectovaginal septum, the pelvic floor, and the perineum. The rapid progress and destructive potential of perineal amoebiasis is noted and the benefits of diagnostic awareness emphasised. Treatment with metronidazo...

journal_title：Archives of disease in childhood

authors： Wynne JM

更新日期：1980-03-01 00:00:00

abstract：:Necrotising enterocolitis occurred in 3 infants after angiography at cardiac catheterisation. It is suggested that hypertonic contrast medium might have been responsible and that this complication could be avoided by the use of nonionic contrast media. ...

journal_title：Archives of disease in childhood

authors： Cooke RW,Meradji M,de Villeneuve VH

更新日期：1980-01-01 00:00:00

abstract：:The concentration of zinc in the hair of 219 schoolchildren aged between 10 and 11 years was measured and related to height, weight, estimates of consumption of zinc-rich foods, number of children living at home, and rank in family. None of the correlation coefficients between hair zinc and the other variables was sig...

journal_title：Archives of disease in childhood

authors： Heinersdorff N,Taylor TG

更新日期：1979-12-01 00:00:00

abstract：:In a study of 256 families, among whom were twins, midparent-adult son correlations for height, weight, and combined skinfold measurements were 0.67, 0.47, and 0.23 respectively. The corresponding midparent-adult daughter correlations were 0.63, 0.42, and 0.24. Midparent-growing offspring correlations were highest for...

journal_title：Archives of disease in childhood

authors： Hawk LJ,Brook CG

更新日期：1979-11-01 00:00:00

abstract：:To assess the bacteriological quality of unpooled expressed breast milk, a pilot bottle sample of each donation was examined before the milk was given to the neonate. Provided the milk did not contain greater than 2500 organisms/ml or potential pathogens it was used unheated. Milk containing between 2500 and 5000 orga...

journal_title：Archives of disease in childhood

authors： Davidson DC,Poll RA,Roberts C

更新日期：1979-10-01 00:00:00

abstract：:Bilateral staghorn renal calculi in a 7-year-old girl with cystinuria were dissolved over a period of 6 months, using a high fluid intake, urinary alkalinisation, and D-penicillamine. Even in children with extensive cystine urolithiasis, medical management may avert the need for surgery. ...

journal_title：Archives of disease in childhood

authors： Van Dugteren GR,Wiggelinkhuizen J

更新日期：1979-10-01 00:00:00

abstract：:The fasting serum cholecystokinin-like activity was measured in 21 infants with pyloric stenosis and in 13 normal controls. No significant difference was found between the two groups. The basal acid secretion was measured by continuously aspirating the previously emptied stomach for one hour. The basal gastric volume ...

journal_title：Archives of disease in childhood

authors： Rogers IM,Drainer IK,Dougal AJ,Black J,Logan R

更新日期：1979-10-01 00:00:00

abstract：:When isolated from the female genital tract, diphtheroids are usually regarded as commensal organisms. Corynebacterium kutscheri however is a pathogen in laboratory rodents. We report a case in which C. kutscheri was isolated as a pure culture from the umbilical cord and from other surface sites in an infant. Histolog...

journal_title：Archives of disease in childhood

authors： Fitter WF,de Sa DJ,Richardson H

更新日期：1979-09-01 00:00:00

abstract：:Unexpected stability of arterial oxygen and carbon dioxide tensions occurred in infants recovering from respiratory distress syndrome (RDS) on the abrupt withdrawal of CPAP at 6 cmH2O pressure. 30 preterm infants (birthweights 880--3200 g gestational ages 29--38 weeks) were treated at a mean age of 10 hours and for a ...

journal_title：Archives of disease in childhood

authors： Hegyi T,Hiatt IM

更新日期：1979-09-01 00:00:00

abstract：:Administration of 1 alpha-OH-D3 to hypocalcaemic neonates (mean +/- SD, serum calcium 1.50 +/- 0.13 mmol/l) significantly increased serum calcium in all 24 infants within 48 hours after starting therapy (mean +/- SD 1.83 +/- 0.23 mmol/1). The time required to correct hypocalcaemia was significantly shorter (2.04 +/- 0...

journal_title：Archives of disease in childhood

authors： Barak Y,Milbauer B,Weisman Y,Edelstein S,Spirer Z

更新日期：1979-08-01 00:00:00

abstract：:Eithe low birthweight infants were studied for their metabolic and hormonal responses to intravenous alimentation when the caloric input was varied. The study was made during three consecutive 12-hour periods, when solutions of glucose, glucose and amino-acids, and glucose and amino-acid and lipids were successively i...

journal_title：Archives of disease in childhood

authors： Rubecz I,Mestyán J,Varga P,Soltész G

更新日期：1979-07-01 00:00:00

abstract：:Copper deficiency is reported in an infant of very low birthweight. It was characterised by extensive bone changes, severe neutropenia, and hypocupraemia. These manifestations could have been missed but for an intercurrent pneumonia which led to an x-ray of the chest. ...

journal_title：Archives of disease in childhood

authors： Yuen P,Lin HJ,Hutchinson JH

更新日期：1979-07-01 00:00:00

abstract：:Chest physiotherapy still remains one of the most important aspects in the treatment of chest complications of cystic fibrosis. A mechanical device that allows the patient with cystic fibrosis to do his own chest physiotherapy will be of great benefit if it is as effective as manual percussion. 14 patients with cystic...

journal_title：Archives of disease in childhood

authors： Maxwell M,Redmond A

更新日期：1979-07-01 00:00:00

abstract：:Three cases of osteoid osteoma and one of benign osteoblastoma in children are described. The main complaint was severe pain which was worse at night; it was relieved by aspirin or other analgesics. The diagnosis was made on clinical and radiological grounds and was confirmed on histological examination of the central...

journal_title：Archives of disease in childhood

authors： Black JA,Levick RK,Sharrard WJ

更新日期：1979-06-01 00:00:00

abstract：:Coeliac disease occurred at the same age in MZ twins. The diagnosis was confirmed by histology of the small intestine, rapid response to a gluten-free diet, and relapse after reintroduction of gluten. ...

journal_title：Archives of disease in childhood

authors： Penna FJ,Mota JA,Roquete ML,de Carvalho AS,de Oliveira Lemos AT,Barbosa AJ,Leao E,Ferreira RA,de Paula Castro L

更新日期：1979-05-01 00:00:00

abstract：:Four patients with salt-losing congenital adrenal hyperplasia (CAH) who had stopped mineralocorticoid therapy for several years, showed raised plasma concentrations of 17OH-progesterone and plasma renin activity, despite adequate glucoticoid therapy. One patient was able to reduce urinary sodium excretion when the sod...

journal_title：Archives of disease in childhood

authors： Hughes IA,Wilton A,Lole CA,Gray OP

更新日期：1979-05-01 00:00:00

abstract：:Significant folate deficiency in 14 out of 37 preterm infants of birthweights 2.0 kg or less was found to be reliably and most conveniently diagnosed by abnormal morphological changes in peripheral blood and confirmed by the response to folic acid. Deficiency appeared to be more common in light-for-dates infants inclu...

journal_title：Archives of disease in childhood

authors： Strelling MK,Blackledge DG,Goodall HB

更新日期：1979-04-01 00:00:00

abstract：:During June and July 1977 5 junior boys in a boarding school for 800 pupils became ill with a mild infection caused by Coxsackie B1. The school had been taking part in a vaccine trial, and paired blood samples had been taken from new entrants in October 1976 and October 1977. 18% of the boys susceptible to the infecti...

journal_title：Archives of disease in childhood

authors： Hoskins TW,Davies JR,Smith AJ,Collingham K,Chamberlain RN

更新日期：1979-04-01 00:00:00

abstract：:The foot length, occipito-frontal head circumference (OFC), crown-rump, and crown-heel length (CHL) of 123 neonates of gestational ages 26-42 weeks, were measured between 12 hours and 5 days. A gauge, designed and constructed at St Mary's Hospital, Manchester, was used to measure foot length. In term babies (37-42 wee...

journal_title：Archives of disease in childhood

authors： James DK,Dryburgh EH,Chiswick ML

更新日期：1979-03-01 00:00:00

abstract：:A case of partial trisomy of the long arm of chromosome 3 (3q21 leads to qter) is described. The clinical findings are compared with those in 5 previously reported cases. There is hirsutism and characteristic facial dysmorphism, the common features of which are a square-shaped face, prominent nasal bridge, everted nos...

journal_title：Archives of disease in childhood

authors： Fear C,Briggs A

更新日期：1979-02-01 00:00:00

abstract：:Somatomedin activity was assayed in the plasma of children suffering from protein calorie malnutrition by a bioassay using rat cartilage and expressed as sulphate uptake ratio. The sulphate uptake ratio was particularly reduced in kwashiorkor. In marasmus there was a slight reduction and the levels were still in the n...

journal_title：Archives of disease in childhood

authors： Mohan PS,Jaya Rao KS

更新日期：1979-01-01 00:00:00

abstract：:During a meningococcal (group A) epidemic, 47 Nigerian children with acute meningococcaemia without meningitis were studied. Their mortality rate was 43% compared with 8% during the whole epidemic. Those presenting with coma and shock had a mortality of 93%, but without shock or coma mortality was only 6%. Coma or sho...

journal_title：Archives of disease in childhood

authors： Lewis LS

更新日期：1979-01-01 00:00:00

abstract：:Two male patients with congenital cleft lip and palate first seen at ages 10.2 and 21.5 years presented with typical signs of hypothalamic-interior pituitary hormone deficiencies. They were found to lack GH, LH, and FSH and to be partially deficient in TSH and ACTH. Several congenital defects may explain this rare syn...

journal_title：Archives of disease in childhood

authors： Roitman A,Laron Z

更新日期：1978-12-01 00:00:00

abstract：:Clinical, radiological, and genetic features are described in 3 patients with hypochondroplasia. Early recognition of this disorder is possible from the abnormal body proportions with short limbs and lumbar lordosis without facial stigmata of achondroplasia. Radiological confirmation is possible provided a full skelet...

journal_title：Archives of disease in childhood

authors： Glasgow JF,Nevin NC,Thomas PS

更新日期：1978-11-01 00:00:00

abstract：:A 6-week-old girl with fever, hypernatraemia, dehydration, and polyuria failed to concentrate urine in response to exogenous vasopressin administration. There was no family history of nephrogenic diabetes insipidus. When she was 15 months old, the infusion of vasopressin did not produce an increase in urinary cyclic-A...

journal_title：Archives of disease in childhood

authors： Schreiner RL,Skafish PR,Anand SK,Northway JD

更新日期：1978-11-01 00:00:00

abstract：:Chromatographic analysis of sugars in the stools of 40 normal newborn infants has shown the presence of an oligosaccharide in 85% of samples. The oligosaccharide has been shown to contain fucose (6-deoxygalactose), glucose, and galactose and is present in normal breast milk. In addition fucose has also been found in t...

journal_title：Archives of disease in childhood

authors： Whyte RK,Homer R,Pennock CA

更新日期：1978-11-01 00:00:00

abstract：:The adrenal glands of 41 fresh stillbirths were studied and a 'stress response' pattern could be seen in 28. In these glands the stress response was characterised by compact cell change, lipid depletion, excess pyroninophilia, and dilatation of the very prominent granular endoplasmic reticulum. Scattered areas of cyto...

journal_title：Archives of disease in childhood

authors： de Sa DJ

更新日期：1978-10-01 00:00:00

abstract：:Three neonates with rectal perforations probably caused by the use of the rectal thermometer, are reported. The dangers of this condition and the difficulty of diagnosis even at laporatomy are emphasised. It is suggested that since the axillary temperature in the neonate is an adequate reflection of the core temperatu...

journal_title：Archives of disease in childhood

authors： Frank JD,Brown S

更新日期：1978-10-01 00:00:00

abstract：:A 5-year-old boy with Cockayne's syndrome is described. In addition to the recognised clinical features, he presented with severe fixed airways obstruction, and investigations confirmed clinical and physiological emphysema. In a disorder associated with many of the features of aging, it is probably that the presence o...

journal_title：Archives of disease in childhood

authors： Cunningham M,Godfrey S,Moffat WM

更新日期：1978-09-01 00:00:00